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3M™ Polisher ST

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3M™ Polisher ST

About the product

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane. The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalized membrane downstream of the functionalized nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.

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Product name and IDs 3M ID Overall Diameter (Imperial) Overall Diameter (Metric) End Modification Micron Rating Flow Rate (Imperial) Overall Height (Imperial) Overall Height (Metric) Flow Rate (Metric) Filter Type Net Weight (Metric) Application Filter Technology Industries Product Series

3M ID

7100228761

Overall Diameter (Imperial)

1.6900 INCH

Overall Diameter (Metric)

4.3000 CENTIMETER

End Modification

Luer Loc

Micron Rating

0.8000 MICROMETER

Flow Rate (Imperial)

0.0010 GALLON_PER_MINUTE

Overall Height (Imperial)

2.3200 INCH

Overall Height (Metric)

5.9000 CENTIMETER

Flow Rate (Metric)

4.0000 MILLILITER_PER_MINUTE

Filter Type

Single Use

Net Weight (Metric)

15.5000 GRAM

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

3M ID

7100228760

Overall Diameter (Imperial)

1.6900 INCH

Overall Diameter (Metric)

4.3000 CENTIMETER

End Modification

Luer Loc

Micron Rating

0.8000 MICROMETER

Flow Rate (Imperial)

0.0000 GALLON_PER_MINUTE

Overall Height (Imperial)

1.8900 INCH

Overall Height (Metric)

4.8000 CENTIMETER

Flow Rate (Metric)

1.0000 MILLILITER_PER_MINUTE

Filter Type

Single Use

Net Weight (Metric)

10.0000 GRAM

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

3M ID

7100182144

Overall Diameter (Imperial)

17.7200 INCH

Overall Diameter (Metric)

45.0000 CENTIMETER

End Modification

1 1/2 in Sanitary Connectors

Micron Rating

0.8000 MICROMETER

Flow Rate (Imperial)

0.0010 GALLON_PER_MINUTE

Overall Height (Imperial)

8.7400 INCH

Overall Height (Metric)

22.2000 CENTIMETER

Flow Rate (Metric)

4.0000 MILLILITER_PER_MINUTE

Filter Type

Single Use

Net Weight (Metric)

12.7000 KILOGRAM

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

3M ID

7100179570

Overall Diameter (Imperial)

17.8000 INCH

Overall Diameter (Metric)

45.2000 CENTIMETER

End Modification

1 1/2 in Sanitary Connectors

Micron Rating

0.8000 MICROMETER

Flow Rate (Imperial)

0.5060 GALLON_PER_MINUTE

Overall Height (Imperial)

3.0300 INCH

Overall Height (Metric)

7.7000 CENTIMETER

Flow Rate (Metric)

2.3000 LITER_PER_MINUTE

Filter Type

Single Use

Net Weight (Metric)

3.8000 KILOGRAM

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

3M ID

7100179560

Overall Diameter (Imperial)

9.4900 INCH

Overall Diameter (Metric)

24.1000 CENTIMETER

End Modification

3/4 in Sanitary Connectors

Micron Rating

0.8000 MICROMETER

Flow Rate (Imperial)

0.2240 GALLON_PER_MINUTE

Overall Height (Imperial)

5.9800 INCH

Overall Height (Metric)

15.2000 CENTIMETER

Flow Rate (Metric)

1020.0000 MILLILITER_PER_MINUTE

Filter Type

Single Use

Net Weight (Metric)

1.8000 KILOGRAM

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Product Details

  • The 3M™ Polisher ST is single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalized membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins

Suggested Applications

  • Performance unaffected by process fluid turbidity up to 40 NTU
  • Residual DNA removal, when present, in process stream

Product Specifications

Industries
Industries

BiopharmaceuticalManufacturing

Net Weight (Metric)
Net Weight (Metric)

1.1000, 1.2000, 1.8000, 10.0000, 12.7000, 15.5000, 3.8000, 72.0000, 78.0000

Filter Technology
Filter Technology

Anion exchange chromatography

Micron Rating
Micron Rating

0.8000

Product Series
Product Series

Polisher ST

Flow Rate (Metric)
Flow Rate (Metric)

25.0000, 4.0000, 1.0000, 1020.0000, 170.0000, 2.3000, 340.0000

Flow Rate (Imperial)
Flow Rate (Imperial)

0.0010, 0.0050, 0.0000, 0.0370, 0.0750, 0.2240, 0.5060

Overall Height (Imperial)
Overall Height (Imperial)

3.9800, 1.8900, 1.9300, 2.3200, 3.0300, 3.3900, 5.9800, 8.7400

Overall Diameter (Imperial)
Overall Diameter (Imperial)

9.4900, 1.6900, 3.0300, 17.7200, 17.8000

Overall Diameter (Metric)
Overall Diameter (Metric)

24.1000, 4.3000, 7.7000, 45.0000, 45.2000

End Modification
End Modification

3/4 in Sanitary Connectors, Luer Loc, 1 1/2 in Sanitary Connectors

Filter Type
Filter Type

Single Use

Application
Application

AnionExchange

Overall Height (Metric)
Overall Height (Metric)

10.1000, 15.2000, 22.2000, 4.8000, 4.9000, 5.9000, 7.7000, 8.6000

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