About the product
We designed the 3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsules with LA Media as single-use depth filtration capsules for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required. These capsules are ideal for lab and scale-up studies. The lenticular design and vertical flow path helps provide consistent performance between formats.
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsules with LA Media is a family of advanced depth filters that are low in extractables and are designed to provide superior clarification of bioprocess, biological, and pharmaceutical fluids. In addition to mechanical filtration, the Zeta Plus LA Series Filter Media exhibits a positive electrokinetic charge that enhances filtration efficiency by removing sub-micron particles through adsorption - the adhesion of particles to the charged filter surface. Zeta Plus LA Series Filter Media provides low levels of inorganic extractables, especially aluminum, making it a premium grade filter media ideal for parenteral, blood fractionation, bioprocess and infant food/formula applications. The Zeta Plus LA Series products are manufactured to stringent quality controls to provide reproducible product performance from filter to filter, lot to lot. When used as a pre-filter, the high contaminant holding capacity of Zeta Plus LA Series Filter Media can prolong the life of the final stage filter.
Zeta Plus LA Series Filter Media is manufactured to controls described in our Drug Master Filer on record with the FDA. Certificates of Quality are included with every filter. These filters meet the requirements of USP <88> Class VI Biological Reactivity Tests and also meet the strict requirements specified in the Drug Master File, including product control and traceability.
When faced with the challenges of filtration for the bioprocessing industry, where upstream cell culture clarification or downstream impurity removal is required, 3M™ Encapsulated Systems provide an ergonomic, easy-to-use solution. Our Scale-Up Capsules also incorporate 3 feet and rubber shoes for a level posture on many surfaces and can be stacked for convenience. The Scale-Up Capsules are available in three sizes to meet our customer's varying volumes and applications and the capsules have been designed for minimal hold-up volume.
We utilize the lenticular filter design and vertical flow path on our Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, which has proven effective for depth filtration systems. A total of four single-use scale-up capsules are available for media grade selection and filter sizing. The BC25 capsule with 25 cm2 filter media is ideal for media grade screening. The Scale-Up Capsule filters with 170 cm2, 340 cm2 and 1020 cm2 media are designed for intermediate scale studies and low volume production filtration. Combined with the larger production scale capsules, the Zeta Plus Encapsulated System offers a completely single-use solution to process from 100 ml to 25,000 L of liquid.
Suggested Applications
Industries |
Industries
Biopharmaceutical manufacturing |
Filter Technology |
Filter Technology
Adsorbent |
Grade |
Grade
90LA |
Product Series |
Product Series
Encapsulated |
Brand |
Brand
Zeta Plus™ |
Overall Length (Imperial) |
Overall Length (Imperial)
5.98 |
Overall Diameter (Imperial) |
Overall Diameter (Imperial)
8.27 |
Overall Width (Metric) |
Overall Width (Metric)
21.6 |
Overall Length (Metric) |
Overall Length (Metric)
15.2 |
Overall Diameter (Metric) |
Overall Diameter (Metric)
21 |
Filter Type |
Filter Type
Depth |
Overall Width (Imperial) |
Overall Width (Imperial)
8.5 |
Application |
Application
Harvest and clarification |